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Long-time period use of metformin could cause a vitamin B12 deficiency, which can lead to extreme tiredness. One of the simplest ways to incorporate apple cider vinegar into your food plan is to use it in cooking. What are the disadvantages of apple cider vinegar? "What actually bothers me is that the diabetes associations here are nonetheless telling diabetes patients to stick with low-fat. Diabetes therapy may be very individualized, noted a February 2022 article in Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. This text examines the evidence behind six potential well being benefits of apple cider vinegar. They also snacked much less for 3-24 hours after consuming the apple cider vinegar. That said, to avoid unintended effects like indigestion or acid reflux at night time, consume it no less than 2-3 hours earlier than bed. A lot vinegar can cause harmful unwanted side effects, including tooth enamel erosion and potential drug interactions. If unintended effects from Tepezza turn out to be tough to tolerate, discuss along with your physician about coping suggestions or different remedy options.